Jul-Dec 2015 | Vol 1 | Issue 1 | Page :31-32
Farhan Ahmad Khan1, Kirti Vishwakarma2, Imtiyaz Ahmad Shah3*
1Professor, 2Assistant Professor, 3*PG student, Department of Pharmacology, Teerthanker Mahaveer Medical College and Research Centre, Moradabad, UP, India..
Adverse drug reactions (ADRs) are one of the leading causes of death among hospitalized patients and occur in 0.3 to 7 per cent of all hospital admissions. These may vary from mild rashes to severe reactions such as Stevens-Johnson syndrome (SJS). SJS is a life-threatening severe cutaneous adverse reaction. We report here a case of phenytoin induced SJS in a 21 year old male reported to a dermatology OPD of Teerthanker hospital Moradabad. The patient responded to the treatment and was prescribed systemic steroids, Inj. Prednisolone 10 mg qid for 7 days, which was gradually tapered to 10 mg tid for 7 days, 10 mg bid for 5 days, then Tab Prednisolone 10 mg once daily for 5days respectively, Benzydyamine hydrochloride 0.15% oral rinse for oral ulcers.
Keywords: :Drug induced Stevens - Johnson syndrome, Adverse Drug reaction, Ciprofloxacin, Diclofenac.